Benzonase

Genetically engineered Benzonase Nuclease from Serratia marcescens degrades all forms of DNA and RNA (single (single-stranded, double-stranded, linear and circular) while having no proteolytic activity. It is effective over a wide range of conditions and possesses an exceptionally high specific activity. It completely digests nucleic acids to 5'-monophosphate terminated oligonucleotides 3 to 5 bases in length (below the hybridization limit), which is ideal for removal of nucleic acids from recombinant proteins enabling compliance with FDA guidelines for nucleic acid contamination.