PEG L-Asparaginase API
- Bulk API
- for IM/IV Administration
for Acute Lymphoblastic Leukemia
Description
Asparaginase is a bacterial enzyme that can specifically degrade L-Asparagine into L-Aspartic acid and Ammonia. Its active form is a homologous tetramer; each subunit is composed of 326 amino acids
Application
PEG L-Asparaginase is a polyethylene glycol-conjugated enzyme used in the treatment of certain malignancies, particularly acute lymphoblastic leukemia, by depleting asparagine levels in the bloodstream. Its formulation as an active pharmaceutical ingredient (API) enhances its therapeutic efficacy and minimizes immunogenicity.
First line treatment for Acute Lymphoblastic Leukaemia. Also used in treatment of patients with acute lymphoblastic leukaemia with hypersensitivity to native forms of L-Asparaginase.
